One saponins, terpenoids, etc.and therapeutically active components

     One of the most valuable components of indigenous medical systems for
over 40 centuries has been Mangifera indica
leaves, the largest fruit-bearing tree ever discovered in India. Mangifera leaves
usage as a medical agent dates back to 327 BCE. Existence of prime groups
of phytochemical constituents such as anthraquinones, saponins, terpenoids, etc.and therapeutically active components
such as mangiferin, friedelin, stigmasterol,
lupeol, etc. was also claimed to be found
in Mangifera indica leaves


Although the scientific information
that can support its success is scarce, the leaves have been traditionally used
as an antibacterial and immunomodulatory
agent. Mangifera indica leaves are also used as an antibacterial agent in
Nigerian folk herbalism. To ascertain
whether or not there is a scientific basis for this use, the effect of the blood glucose level was evaluated in normoglycaemic, glucose-induced
hyperglycaemic and streptozotocin (STZ)
induced diabetic rodents such as Rattus (rat). The aqueous extract given orally
did not modify the blood glucose levels in either normoglycaemic or STZ-induced
(streptozotocin) diabetic rodents specifically Rattus (rat).

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Aqueous extracts of Mangifera indica leaves showed remarkable influence on reproductive functions,
wound regeneration and antidiabetic tasks. Alcoholic extracts of Mangifera
indica leaves have been found containing TNF- (Tumor necrosis factor), ILIB
expression and B-lactamase producing enteric
bacterial development.


     Mangifera indica leaves are equipped with
a broad outer cuticle to avoid the loss of nutrients
and to prevent wetting when it’s
raining. Furthermore, Mangifera indica
leaves are found alternating on the plant stalk to exploit the light energy acquired from the sun. This is because of the
fact that Mangifera indica develops best when exposed to sunlight.


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